Bioanalysis without Sample Cleanup or Chromatography: The Evaluation and Initial Implementation of Direct Analysis in Real Time Ionization Mass Spectrometry for the Quantification of Drugs in Biological Matrixes-Reference-Cited by-同舟云学术

Bioanalysis without Sample Cleanup or Chromatography: The Evaluation and Initial Implementation of Direct Analysis in Real Time Ionization Mass Spectrometry for the Quantification of Drugs in Biological Matrixes

Published:2008-12-03 Issue:1 Volume:81 Page:193-202
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Yu Shaoxia¹,Crawford Elizabeth¹,Tice Joe¹,Musselman Brian¹,Wu Jing-Tao¹

Affiliation:

1. Department of Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts 02139, and IonSense, Inc., Saugus, Massachusetts 01906

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac801734t

Reference19 articles.

1. Strategy of Utilizing In Vitro and In Vivo ADME Tools for Lead Optimization and Drug Candidate Selection

2. High throughput liquid chromatography/mass spectrometry bioanalysis using 96-well disk solid phase extraction plate for the sample preparation

3. Evaluation of 384-well formatted sample preparation technologies for regulated bioanalysis

4. High-throughput quantification for a drug mixture in rat plasma – a comparison of Ultra Performance™ liquid chromatography/tandem mass spectrometry with high-performance liquid chromatography/tandem mass spectrometry

5. High-speed liquid chromatography/tandem mass spectrometry using a monolithic column for high-throughput bioanalysis

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