Total Synthesis of 2‴,5‴-Diepisilvestrol and Its C1‴ Epimer: Key Structure Activity Relationships at C1‴ and C2‴-Reference-Cited by-同舟云学术

Total Synthesis of 2‴,5‴-Diepisilvestrol and Its C1‴ Epimer: Key Structure Activity Relationships at C1‴ and C2‴

Published:2012-07-20 Issue:8 Volume:75 Page:1500-1504
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Chambers Jennifer M.¹,Huang David C. S.²,Lindqvist Lisa M.²,Savage G. Paul³,White Jonathan M.¹,Rizzacasa Mark A.¹

Affiliation:

1. School of Chemistry, The Bio21 Institute, The University of Melbourne, Victoria 3010, Australia

2. Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, and Department of Medical Biology, University of Melbourne, Victoria 3010, Australia

3. CSIRO Molecular and Health Technologies, Bayview Avenue, Victoria 3168, Australia

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np300376f

Reference22 articles.

1. Meurer-Grimes, B. M.; Yu, J.; Vairo, G. L.U.S patent 6710075 B2, 2004.

2. Silvestrol and Episilvestrol, Potential Anticancer Rocaglate Derivatives from Aglaia silvestris

3. Silvestrol and Episilvestrol, Potential Anticancer Rocaglate Derivatives from Aglaia silvestris.

4. Chemistry and Biological Activity of Rocaglamide Derivatives and Related Compounds in Aglaia Species (Meliaceae)

5. Biomimetic synthesis of the novel 1,4-dioxanyloxy fragment of silvestrol and episilvestrol

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