CO2-Driven Nebulization of pH-Sensitive Supramolecular Polymers for Intraperitoneal Hydrogel Formation and the Treatment of Peritoneal Metastasis

Author:

Braet Helena12,Fransen Peter-Paul3,Mariën Remco1,Lollo Giovanna4,Ceelen Wim25,Vervaet Chris1,Balcaen Lieve6,Vanhaecke Frank26ORCID,Vanhove Christian27ORCID,van der Vegte Stefan8,Gasthuys Elke9,Vermeulen An9,Dankers Patricia Y.W.10ORCID,De Smedt Stefaan C.12ORCID,Remaut Katrien12ORCID

Affiliation:

1. Department of Pharmaceutics, Ghent University, Ghent 9000, Belgium

2. CRIG − Cancer Research Institute Ghent, Ghent 9000, Belgium

3. UPyTher BV, Eindhoven 5600 MB, The Netherlands

4. Laboratoire d’Automatique, de Génie des Procédés et de Génie Pharmaceutique (LAGEPP), Université Claude Bernard Lyon 1, Lyon 69622, France

5. Department of Human Structure and Repair, Ghent University, Ghent 9000, Belgium

6. Department of Chemistry, Ghent University, Ghent 9000, Belgium

7. Department of Electronics and Information Systems, Ghent University, Ghent 9000, Belgium

8. Medspray b.v., Enschede 7521 PV, The Netherlands

9. Department of Bioanalysis, Ghent University, Ghent 9000, Belgium

10. Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven 5600 MB, The Netherlands

Funder

Universiteit Gent

Fonds Wetenschappelijk Onderzoek

H2020 Health

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

Reference70 articles.

1. Development of Peritoneal Carcinomatosis in Epithelial Ovarian Cancer: A Review

2. Epithelial ovarian cancer

3. Ovarian Cancer Survival Rates | Ovarian Cancer Prognosis. American Cancer Society. https://www.cancer.org/cancer/ovarian-cancer/detection-diagnosis-staging/survival-rates.html (accessed 2022-03-03).

4. Global cancer statistics

5. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

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