Apoptotic Neutrophil Membrane-Camouflaged Liposomes for Dually Targeting Synovial Macrophages and Fibroblasts to Attenuate Osteoarthritis

Author:

Deng Caifeng12,Chen Yuxiao12,Zhao Xuan12,Yu Liukang12,Xiao Yongbing12,Li Hui12,Zhang Yuqing34,Ai Kelong5ORCID,Zhou Dongfang6ORCID,Bai Xiaochun7,Gong Tao8,Wei Jie129,Zeng Chao1210,Lei Guanghua1210ORCID

Affiliation:

1. Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha 410008, China

2. Hunan Key Laboratory of Joint Degeneration and Injury, Changsha 410008, China

3. Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States

4. The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States

5. Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410078, China

6. NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China

7. Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China

8. Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610064, China

9. Health Management Center, Xiangya Hospital, Central South University, Changsha 410008, China

10. National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China

Funder

Central South University

Natural Science Foundation of Hunan Province

National Key Research and Development Program of China

China Postdoctoral Science Foundation

Science and Technology Program of Hunan Province

National Natural Science Foundation of China

Key Research and Development Program of Hunan Province of China

National Clinical Research Center for Geriatric Disorders

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

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