The Binding of Fe(II)–Heme to the Amyloid Beta Peptide of Alzheimer’s Disease: QM/MM Investigations
Author:
Affiliation:
1. Department of Chemistry, The University of Calgary, Calgary, Alberta, Canada T2N 1N4
Publisher
American Chemical Society (ACS)
Subject
Physical and Theoretical Chemistry,Computer Science Applications
Link
https://pubs.acs.org/doi/pdf/10.1021/ct300716p
Reference36 articles.
1. An overview of the biochemistry of Alzheimer’s disease is available athttp://en.wikipedia.org/wiki/Biochemistry_of_Alzheimer’s_disease(accessed September 2012).
2. Amyloid-beta peptide binds with heme to form a peroxidase: Relationship to the cytopathologies of Alzheimer's disease
3. Heme–Cu Bound Aβ Peptides: Spectroscopic Characterization, Reactivity, and Relevance to Alzheimer’s Disease
4. N-Terminal Deletions Modify the Cu2+ Binding Site in Amyloid-β
5. Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide
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