On the Antibiotic and Antifungal Activity of Pestalone, Pestalachloride A, and Structurally Related Compounds

Author:

Augner Daniel1,Krut Oleg2,Slavov Nikolay1,Gerbino Dario C.1,Sahl Hans-Georg3,Benting Jürgen4,Nising Carl F.4,Hillebrand Stefan4,Krönke Martin2,Schmalz Hans-Günther1

Affiliation:

1. Department of Chemistry, University of Cologne, Greinstrasse 4, 50939 Köln, Germany

2. Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Goldenfelsstrasse 19-21, 50935 Köln, Germany

3. Institute for Medical Microbiology, Immunology and Parasitology, University of Bonn, Meckenheimer Allee 168, 53155 Bonn, Germany

4. Bayer CropScience, Research−Chemistry Disease Control, Alfred-Nobel-Strasse 50, 40789 Monheim, Germany

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Reference15 articles.

1. Pestalone, a New Antibiotic Produced by a Marine Fungus in Response to Bacterial Challenge

2. A closely related structure, formally derived from1by cleavage (O-demethylation) of the methoxy group, was reported:Wachi, Y.; Yamashita, T.; Komatsu, K.; Yoshida, S.JP Patent, JKXXAF JP 07061950 A2 19950307, 1995.

3. Marine natural products and their potential applications as anti-infective agents

4. Triggering cryptic natural product biosynthesis in microorganisms

5. Mixed fermentation for natural product drug discovery

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