Experimental and Computational Screening Models for the Prediction of Intestinal Drug Absorption-Reference-Cited by-同舟云学术

Experimental and Computational Screening Models for the Prediction of Intestinal Drug Absorption

Published:2001-05-16 Issue:12 Volume:44 Page:1927-1937
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Stenberg Patric¹,Norinder Ulf¹,Luthman Kristina¹,Artursson Per¹

Affiliation:

1. Department of Pharmaceutics, Uppsala Biomedical Center, Uppsala University, P.O. Box 580, SE-751 23 Uppsala, Sweden; Department of Medicinal Chemistry, AstraZeneca Research and Development, SE-151 85 Södertälje, Sweden; and Department of Medicinal Chemistry, Institute of Pharmacy, University of Tromsø, N-9037 Tromsø, Norway

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm001101a

Reference45 articles.

1. Managing the drug discovery/development interface

2. Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985).

3. Virtual screening of intestinal drug permeability

4. A method for the determination of cellular permeability coefficients and aqueous boundary layer thickness in monolayers of intestinal epithelial ( Caco-2) cells grown in permeable filter chambers

5. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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