Structure-Based Design, Synthesis, and Biological Evaluation of Novel Pyrrolyl Aryl Sulfones: HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors Active at Nanomolar Concentrations-Reference-Cited by-同舟云学术

Structure-Based Design, Synthesis, and Biological Evaluation of Novel Pyrrolyl Aryl Sulfones: HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors Active at Nanomolar Concentrations

Published:2000-04-14 Issue:9 Volume:43 Page:1886-1891
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Artico Marino¹,Silvestri Romano¹,Pagnozzi Eugenia¹,Bruno Biancamaria¹,Novellino Ettore¹,Greco Giovanni¹,Massa Silvio¹,Ettorre Alessandro¹,Loi Anna Giulia¹,Scintu Franca¹,La Colla Paolo¹

Affiliation:

1. Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Studi Farmaceutici, Università degli Studi di Roma “La Sapienza”, P.le A. Moro 5, BOX 36 - ROMA 62, I-00185 Roma, Italy, Dipartimento di Chimica Farmaceutica e Tossicologica, Università degli Studi di Napoli “Federico II”, Via D. Montesano 49, I-80131 Napoli, Italy, Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Banchi di Sotto 55, I-53100 Siena, Italy, Menarini Ricerche SpA, Via T. Speri 10, 00040 Pomezia, Roma,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9901125

Reference16 articles.

1. Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase

2. Synthesis of Pyrryl Aryl Sulfones Targeted at the HIV-1 Reverse Transcriptase

3. 2-Sulfonyl-4-chloroanilino Moiety: A Potent Pharmacophore for the Anti-Human Immunodeficiency Virus Type 1 Activity of Pyrrolyl Aryl Sulfones

4. Validation of the general purpose tripos 5.2 force field

Cited by 137 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ligand‐Free Copper(0)‐Catalyzed C−S Ullmann‐Type Cross‐Coupling Reaction: S‐Arylation of 5,4‐Disubstituted 2,4‐Dihydro‐3H‐1,2,4‐triazole‐3‐thiones;European Journal of Organic Chemistry;2024-04-11

2. Copper(I)-catalyzed interrupted click/radical relay: A four-component modular synthesis of triazole sulfones;Chinese Chemical Letters;2024-03

3. Synthesis, Thermal Stability and Antifungal Evaluation of Two New Pyrrole Esters;Chemistry & Biodiversity;2024-02

4. Electrochemical synthesis of sulfinic and sulfonic esters from sulfonyl hydrazides;Organic & Biomolecular Chemistry;2024

5. Photocatalytic fixation and oxygenation of NAD⁺/NADP⁺ and sulfides using solar light: Exploring mechanistic investigations and their impact on synthetic applications;Photochemistry and Photobiology;2023-12-06