Identification of Less Lipophilic Riminophenazine Derivatives for the Treatment of Drug-Resistant Tuberculosis-Reference-Cited by-同舟云学术

Identification of Less Lipophilic Riminophenazine Derivatives for the Treatment of Drug-Resistant Tuberculosis

Published:2012-09-20 Issue:19 Volume:55 Page:8409-8417
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Dongfeng¹,Lu Yu²,Liu Kai¹,Liu Binna¹,Wang Jingbin¹,Zhang Gang¹,Zhang Hao¹,Liu Yang¹,Wang Bin²,Zheng Meiqin²,Fu Lei²,Hou Yanyan¹,Gong Ningbo¹,Lv Yang¹,Li Chun¹,Cooper Christopher B.³,Upton Anna M.³,Yin Dali¹,Ma Zhenkun³,Huang Haihong¹

Affiliation:

1. State Key Laboratory of Bioactive Substances and Function of Natural Medicine & Beijing Key Laboratory of Active Substances Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, P. R. China

2. Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, 97 Ma Chang Street, Beijing 101149, P. R. China

3. Global Alliance for TB Drug Development, 40 Wall Street, New York, New York 10005, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300828h

Reference26 articles.

1. World Health Organization. Multidrug and Extensive Drug Resistant Tuberculosis: 2010 Global Report on Surveillance and Response;World Health Organization:Geneva, 2010.

2. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis

3. Synthesis and Structure−Activity Studies of Biphenyl Analogues of the Tuberculosis Drug (6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

4. The challenge of new drug discovery for tuberculosis

5. A New Series of Phenazines (Rimino-Compounds) With High Antituberculosis Activity

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