Stereospecific Synthesis, Structure−Activity Relationship, and Oral Bioavailability of Tetrahydropyrimidin-2-one HIV Protease Inhibitors
Author:
Affiliation:
1. DuPont Pharmaceuticals Company, Wilmington, Delaware 19880-0500
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm9803626
Reference27 articles.
1. L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor.
2. ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.
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