Regioselective Quinazolinone-Directed Ortho Lithiation of Quinazolinoylquinoline: Practical Synthesis of Naturally Occurring Human DNA Topoisomerase I Poison Luotonin A and Luotonins B and E
Author:
Affiliation:
1. Combi Chem-Bio Resource Center, Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune 411 008, India %argade@dalton.ncl.res.in
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo040153v
Reference52 articles.
1. Advances in the directed metallation of azines and diazines (pyridines, pyrimidines, pyrazines, pyridazines, quinolines, benzodiazines and carbolines). Part 1: Metallation of pyridines, quinolines and carbolines
2. Synthesis of Substituted Quinazolin-4(3H)-ones and Quinazolines via Directed Lithiation
3. Directed ortho metalation. Tertiary amide and O-carbamate directors in synthetic strategies for polysubstituted aromatics
4. Metalation and electrophilic substitution of amine derivatives adjacent to nitrogen: .alpha.-metallo amine synthetic equivalents
5. The Carboxylic Acid Group as an Effective Director of Ortho-Lithiation
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