U-Shape Pillar Strip for 3D Cell-Lumped Organoid Model (3D-COM) Mimicking Lung Cancer Hypoxia Conditions in High-Throughput Screening (HTS)

Author:

Lee Sang-Yun12,Lee Eunyoung3,Lim Jeong Uk4,Ku Bosung1,Seong Yu-Jeong2,Ryu Ji-O2,Cho Hyeong Jun35,Kim Kyuhwan35,Hwang Yongki35,Moon Seok Whan6,Moon Mi Hyoung6,Kim Kyung Soo6,Hyun Kwanyong6,Kim Tae-Jung7,Sung Yeoun Eun7,Choi Joon Young8,Park Chan Kwon4,Kim Sung Won910,Yeo Chang Dong11,Kim Seung Joon35,Lee Dong Woo2ORCID

Affiliation:

1. Central R & D Center, Medical & Bio Decision (MBD) Co., Ltd, Suwon 16229, Republic of Korea

2. Department of Biomedical Engineering, Gachon University, Seongnam 13120, Republic of Korea

3. Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

4. Division of Pulmonary, Critical Care and Allergy, Department of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

5. Postech-Catholic Biomedical Engineering Institute, Songeui Multiplex Hall, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

6. Department of Thoracic and Cardiovascular Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

7. Department of Hospital Pathology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

8. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

9. Department of Otorhinolaryngology-Head and Neck Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

10. Department of Biomedicine & Health Sciences, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

11. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea

Funder

National Research Foundation of Korea

Ministry of Trade, Industry and Energy

the National Research Foundation of Korea (NRF) grant fund-ed by the Korean government (MSIT)

the National Research Foundation of Korea (NRF) grant fund-ed by the Korea government (MSIT)

Publisher

American Chemical Society (ACS)

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