Comprehensive Detection of PD-L1 Protein and mRNA in Tumor Cells and Extracellular Vesicles through a Real-Time qPCR Assay-Reference-Cited by-同舟云学术

Comprehensive Detection of PD-L1 Protein and mRNA in Tumor Cells and Extracellular Vesicles through a Real-Time qPCR Assay

Published:2023-07-10 Issue:28 Volume:95 Page:10625-10633
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Peng Wenbo¹,Sun Danyang¹,Lu Wei²,Yin Shenyi³,Ye Buqing³,Wang Xiaoqi¹,Ren Yongan¹,Hong Zichen¹,Zhu Wenyu⁴,Yu Pengfei⁵,Xi Jianzhong Jeff³,Yao Bo¹^ORCID

Affiliation:

1. Department of Chemistry, Zhejiang University, Hangzhou 310058, China

2. GeneX (Zhejiang) Precision Medicine Co., Ltd, Hangzhou 311100, China

3. College of Future Technology, Peking University, Beijing 100871, China

4. Department of Oncology, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213000, China

5. Department of Gastric Surgery, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c00975

Reference39 articles.

1. Cancer immunotherapy: Pros, cons and beyond

2. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

3. Quantitative Assessment of the Heterogeneity of PD-L1 Expression in Non–Small-Cell Lung Cancer

4. Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab

5. Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory

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