Semisynthesis, Antiplasmodial Activity, and Mechanism of Action Studies of Isocoumarin Derivatives

Author:

Coronado Lorena1,Zhang Xue-Qing234,Dorta Doriana1,Escala Nerea15,Pineda Laura M.1,Ng Michelle G.1,del Olmo Esther5,Wang Chang-Yun23ORCID,Gu Yu-Cheng6ORCID,Shao Chang-Lun23ORCID,Spadafora Carmenza1ORCID

Affiliation:

1. Center of Cellular and Molecular Biology of Diseases, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, City of Knowledge, Clayton, Apartado 0816-02852, Panama

2. Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People’s Republic of China

3. Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266200, People’s Republic of China

4. Hubei Key Laboratory of Natural Product Research and Development (China Three Gorges University), College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, People’s Republic of China

5. Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, s/n, E-37007 Salamanca, Spain

6. Syngenta Jealott’s Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, United Kingdom

Funder

Ministry of Education of the People's Republic of China

Taishan Scholar Project of Shandong Province

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Secretaria Nacional de Ciencia y Tecnolog?a

Qingdao National Laboratory for Marine Science and Technology

National System of Investigation of Panama

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

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