High Plasticity of the Amicetin Biosynthetic Pathway in <i>Streptomyces</i> sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin-Reference-Cited by-同舟云学术

High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin

Published:2022-03-09 Issue:3 Volume:85 Page:530-539
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Aryal Niraj¹,Chen Junhong¹,Bhattarai Keshab¹,Hennrich Oliver²,Handayani Ira³,Kramer Markus⁴,Straetener Jan²,Wommer Tatjana²,Berscheid Anne²^ORCID,Peter Silke⁵⁶,Reiling Norbert⁷⁸^ORCID,Brötz-Oesterhelt Heike²⁶^ORCID,Geibel Christian⁹,Lämmerhofer Michael⁹^ORCID,Mast Yvonne⁶¹⁰,Gross Harald¹⁶^ORCID

Affiliation:

1. Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, 72076 Tübingen, Germany

2. Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, Tübingen (IMIT), Cluster of Excellence ‘Controlling Microbes to Fight Infections’, University of Tübingen, 72076 Tübingen, Germany

3. Research Center for Biotechnology, National Research and Innovation Agency of Indonesia (RC Biotechnology BRIN), Jl.Raya Bogor Km.46, Cibinong, 16911, Bogor, West Java, Indonesia

4. Institute of Organic Chemistry, University of Tübingen, 72076 Tübingen, Germany

5. Institute of Medical Microbiology and Hygiene, University of Tübingen, 72076 Tübingen, Germany

6. German Center for Infection Research (DZIF), partner site Tübingen, 72076 Tübingen, Germany

7. Microbial Interface Biology, Research Center Borstel, Leibniz Lung Center, Parkallee 22, 23845 Borstel, Germany

8. German Center for Infection Research (DZIF), partner site Hamburg-Lübeck-Borstel-Riems, 20095 Hamburg, Germany

9. Pharmaceutical Institute, Department of Pharmaceutical Analysis and Bioanalysis, University of Tübingen, 72076 Tübingen, Germany

10. Department of Bioresources for Bioeconomy and Health Research, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany

Funder

Bundesministerium fÃ¼r Bildung und Forschung

Deutscher Akademischer Austauschdienst

Deutsche Forschungsgemeinschaft

Baden-WÃ¼rttemberg Stiftung

Deutsches Zentrum fÃ¼r Infektionsforschung

World Bank Group

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

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