Leishmania major Pteridine Reductase 1 Belongs to the Short Chain Dehydrogenase Family: Stereochemical and Kinetic Evidence-Reference-Cited by-同舟云学术

Leishmania major Pteridine Reductase 1 Belongs to the Short Chain Dehydrogenase Family: Stereochemical and Kinetic Evidence

Published:1998-03-01 Issue:12 Volume:37 Page:4093-4104
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Luba James¹,Nare Bakela¹,Liang Po-Huang¹,Anderson Karen S.¹,Beverley Stephen M.¹,Hardy Larry W.¹

Affiliation:

1. Department of Pharmacology and Molecular Toxicology, University of Massachusetts Medical Center, 55 Lake Avenue North, Worcester, Massachusetts 01605, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, and Department of Pharmacology, 333 Cedar Street, Yale University School of Medicine, New Haven, Connecticut 06520-8066

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi972693a

Reference67 articles.

1. A member of the aldoketo reductase family confers methotrexate resistance in Leishmania.

2. A novel antifolate resistance gene on the amplified H circle of Leishmania.

3. The Roles of Pteridine Reductase 1 and Dihydrofolate Reductase-Thymidylate Synthase in Pteridine Metabolism in the Protozoan Parasite Leishmania major

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