E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance-Reference-Cited by-同舟云学术

E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance

Published:2023-01-05 Issue:2 Volume:145 Page:1176-1184
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Hanzl Alexander¹^ORCID,Barone Eleonora¹,Bauer Sophie¹,Yue Hong²³,Nowak Radosław P.²³^ORCID,Hahn Elisa¹,Pankevich Eugenia V.¹,Koren Anna¹,Kubicek Stefan¹,Fischer Eric S.²³^ORCID,Winter Georg E.¹^ORCID

Affiliation:

1. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria

2. Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States

3. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States

Funder

Austrian Science Fund

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c10784

Reference48 articles.

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5. Development of targeted protein degradation therapeutics

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