Structure–Relaxivity Mechanism of an Ultrasmall Ferrite Nanoparticle T1 MR Contrast Agent: The Impact of Dopants Controlled Crystalline Core and Surface Disordered Shell

Author:

Miao Yuqing1ORCID,Zhang Huan1,Cai Jing2,Chen Yimin1,Ma Huijun3,Zhang Shuo4ORCID,Yi Jia Bao5ORCID,Liu Xiaoli6,Bay Boon-Huat7,Guo Yingkun8,Zhou Xin9ORCID,Gu Ning10ORCID,Fan Haiming1ORCID

Affiliation:

1. Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi’an 710069, China

2. State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China

3. National Demonstration Center for Experimental Chemistry Education, College of Chemistry and Materials Science, Northwest University, Xi’an 710069, China

4. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201204, China

5. Global Innovative Centre for Advanced Nanomaterials, School of Engineering, The University of Newcastle, Callaghan, New South Wales 2308, Australia

6. Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi’an, 710069, China

7. Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, MD10, 117594, Singapore

8. , Key Lab Birth Defects & Related Dis Women & Child of the Ministry of Education, Department of Radiology, Sichuan University, West China University Hospital 2, 20 Sect 3 South Renmin Road, Chengdu 610041, China

9. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, China

10. State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China

Funder

China Postdoctoral Science Foundation

Australian Research Council

National Natural Science Foundation of China

Shaanxi Province

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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