A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation

Author:

Paunovska Kalina1,Sago Cory D.1,Monaco Christopher M.12,Hudson William H.3,Castro Marielena Gamboa1,Rudoltz Tobi G.1,Kalathoor Sujay1,Vanover Daryll A.1,Santangelo Philip J.1,Ahmed Rafi3,Bryksin Anton V.4,Dahlman James E.1ORCID

Affiliation:

1. Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia 30332, United States

2. School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States

3. Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30317, United States

4. Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, United States

Funder

Georgia Institute of Technology

National Parkinson Foundation

Bayer HealthCare

Cystic Fibrosis Foundation

Cancer Research Institute

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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