Function Follows Form: Oriented Substrate Nanotopography Overrides Neurite-Repulsive Schwann Cell–Astrocyte Barrier Formation in an In Vitro Model of Glial Scarring

Author:

Achenbach Pascal12ORCID,Hillerbrand Laura3,Gerardo-Nava José L.45,Dievernich Axel6ORCID,Hodde Dorothee27,Sechi Antonio S.8,Dalton Paul D.9ORCID,Pich Andrij410ORCID,Weis Joachim2,Altinova Haktan211,Brook Gary A.2

Affiliation:

1. Department of Neurology, RWTH Aachen University Hospital, 52074 Aachen, Germany

2. Institute of Neuropathology, RWTH Aachen University Hospital, 52074 Aachen, Germany

3. Department of Functional Materials in Medicine and Dentistry, University Hospital Würzburg, 97070 Würzburg, Germany

4. DWI - Leibniz Institute for Interactive Materials, 52074 Aachen, Germany

5. Advanced Materials for Biomedicine (AMB), Institute of Applied Medical Engineering (AME), RWTH Aachen University Hospital, 52074 Aachen, Germany

6. FEG Textiltechnik Forschungs- und Entwicklungsgesellschaft mbH, 52070 Aachen, Germany

7. University Hospital, Ludwig Maximilian University of Munich, 81377 Munich, Germany

8. Department of Cell and Tumor Biology, RWTH Aachen University Hospital, 52074 Aachen, Germany

9. Phil and Penny Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon 97403, United States

10. Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, 52074 Aachen, Germany

11. Department of Neurosurgery, RWTH Aachen University Hospital, 52074 Aachen, Germany

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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