Discovery of 5-Benzyl-3-phenyl-4,5-dihydroisoxazoles and 5-Benzyl-3-phenyl-1,4,2-dioxazoles as Potent Firefly Luciferase Inhibitors
Author:
Affiliation:
1. A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211Kuopio, Finland
2. Department of Chemistry, University of Jyväskylä, P.O. Box 35, FI-40014 Jyväskylä, Finland
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm301516q
Reference39 articles.
1. Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology
2. Apparent activity in high-throughput screening: origins of compound-dependent assay interference
3. MECHANISM OF BIOLUMINESCENCE, CHEMI-LUMINESCENCE AND ENZYME FUNCTION IN THE OXIDATION OF FIREFLY LUCIFERIN*,†
4. False Positives in a Reporter Gene Assay: Identification and Synthesis of Substituted N-Pyridin-2-ylbenzamides as Competitive Inhibitors of Firefly Luciferase
5. Resveratrol inhibits firefly luciferase
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