Structure-Based Design and Development of Functionalized Mercaptoguanine Derivatives as Inhibitors of the Folate Biosynthesis Pathway Enzyme 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus-Reference-Cited by-同舟云学术

Structure-Based Design and Development of Functionalized Mercaptoguanine Derivatives as Inhibitors of the Folate Biosynthesis Pathway Enzyme 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus

Published:2014-11-12 Issue:22 Volume:57 Page:9612-9626
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dennis Matthew L.¹²,Chhabra Sandeep¹²,Wang Zhong-Chang¹³,Debono Aaron¹,Dolezal Olan²,Newman Janet²,Pitcher Noel P.¹,Rahmani Raphael¹,Cleary Ben¹,Barlow Nicholas¹,Hattarki Meghan²,Graham Bim¹,Peat Thomas S.²,Baell Jonathan B.¹,Swarbrick James D.¹

Affiliation:

1. Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia

2. CSIRO Biosciences Program, Parkville, Victoria 3052, Australia

3. State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, People’s Republic of China

Funder

National Health and Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501417f