Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals-Reference-Cited by-同舟云学术

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Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals

Published:2024-02-26 Issue:3 Volume:37 Page:465-475
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Thienpont Anouck¹²^ORCID,Cho Eunnara³,Williams Andrew³,Meier Matthew J.³,Yauk Carole L.⁴,Rogiers Vera¹,Vanhaecke Tamara¹,Mertens Birgit²

Affiliation:

1. Department of In Vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel (VUB), 1090 Brussels, Belgium

2. Department of Chemical and Physical Health Risks, Sciensano, 1050 Brussels, Belgium

3. Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON K1A 0K9, Canada

4. Department of Biology, University of Ottawa, Ottawa, ON K1N 6N5, Canada

Funder

Canada Foundation for Innovation

Vrije Universiteit Brussel

Canada Research Chairs

Vlaamse regering

Fonds Wetenschappelijk Onderzoek

Horizon 2020 Framework Programme

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.3c00318

Reference50 articles.

1. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

2. Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type

3. Retrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000–12)

4. Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose

5. Genotoxicity testing: Moving beyond qualitative “screen and bin” approach towards characterization of dose-response and thresholds

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Progress in toxicogenomics to protect human health;Nature Reviews Genetics;2024-09-02

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