CYP3A Activation and Glutathione Depletion Aggravate Emodin-Induced Liver Injury
Author:
Affiliation:
1. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
2. Nanjing Forestry University, Nanjing, China
Funder
Natural Science Foundation of Jiangsu Province
National Natural Science Foundation of China
Priority Academic Program Development of Jiangsu Higher Education Institutions
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.8b00117
Reference34 articles.
1. Evaluation of the antibacterial activity ofVentilago madraspatana Gaertn.,Rubia cordifolia Linn. andLantana camara Linn.: isolation of emodin and physcion as active antibacterial agents
2. Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway
3. Activity-Guided Chemo Toxic Profiling of Cassia occidentalis (CO) Seeds: Detection of Toxic Compounds in Body Fluids of CO-Exposed Patients and Experimental Rats
4. Inflammatory stress potentiates emodin-induced liver injury in rats
5. Assessment of the renal protection and hepatotoxicity of rhubarb extract in rats
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