HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins-Reference-Cited by-同舟云学术

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HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

Published:2015-06-23 Issue:8 Volume:10 Page:1831-1837
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Buckley Dennis L.,Raina Kanak,Darricarrere Nicole,Hines John,Gustafson Jeffrey L.,Smith Ian E.¹,Miah Afjal H.¹,Harling John D.¹,Crews Craig M.

Affiliation:

1. Protein Degradation Discovery Performance Unit, GlaxoSmithKline, Stevenage, SG1 2NY, United Kingdom

Funder

National Institute of Allergy and Infectious Diseases

Congressionally Directed Medical Research Programs

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.5b00442

Reference39 articles.

1. Small-Molecule Control of Intracellular Protein Levels through Modulation of the Ubiquitin Proteasome System

2. Protacs for Treatment of Cancer

3. Conditional Control of Protein Function

4. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

5. Chemical Genetic Control of Protein Levels: Selective in Vivo Targeted Degradation

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