Creation of (R)-Amine Transaminase Activity within an α-Amino Acid Transaminase Scaffold-Reference-Cited by-同舟云学术

Creation of (R)-Amine Transaminase Activity within an α-Amino Acid Transaminase Scaffold

Published:2020-01-28 Issue:2 Volume:15 Page:416-424
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Voss Moritz¹,Xiang Chao¹,Esque Jérémy²,Nobili Alberto¹,Menke Marian J.¹,André Isabelle²^ORCID,Höhne Matthias³^ORCID,Bornscheuer Uwe T.¹^ORCID

Affiliation:

1. Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, Greifswald University, Felix-Hausdorff-Strasse 4, 17487 Greifswald, Germany

2. Toulouse Biotechnology Institute (TBI), Université de Toulouse, CNRS, INRA, INSA, 135, Avenue de Rangueil, F-31077 Toulouse cedex 04, France

3. Protein Biochemistry, Institute of Biochemistry, Greifswald University, Felix-Hausdorff-Strasse 4, 17487 Greifswald, Germany

Funder

FP7 Food, Agriculture and Fisheries, Biotechnology

Deutsche Forschungsgemeinschaft

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00888

Reference45 articles.

1. Pyridoxal Phosphate Enzymes: Mechanistic, Structural, and Evolutionary Considerations

2. Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications

3. Kinetic Studies of Glutamic Oxaloacetic Transaminase Isozymes*

4. Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

5. Transaminases for chiral amine synthesis

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