Discovery of a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia-Reference-Cited by-同舟云学术

Discovery of a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia

Published:2010-12-08 Issue:2 Volume:2 Page:171-176
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Qin Jun¹,Rao Ashwin¹,Chen Xiao¹,Zhu Xiaohong¹,Liu Zhidan¹,Huang Xianhai¹,Degrado Sylvia¹,Huang Ying¹,Xiao Dong¹,Aslanian Robert¹,Cheewatrakoolpong Boonlert²,Zhang Hongtao²,Greenfeder Scott²,Farley Constance²,Cook John²,Kurowski Stan²,Li Qiu²,van Heek Margaret²,Chintala Madhu²,Wang Ganfeng³,Hsieh Yunsheng³,Li Fangbiao³,Palani Anandan¹

Affiliation:

1. Department of Medicinal Chemistry

2. Department of Biology

3. Department of Drug Metabolism & Pharmacokinetics, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml100251u

Reference31 articles.

1. Influence of nicotinic acid on serum cholesterol in man

2. Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review

3. Low High-Density Lipoprotein Cholesterol as a Risk Factor in Coronary Heart Disease

4. Nicotinic Acid Receptor Agonists

5. GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole–tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a

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