Design and Synthesis of Potent and Multifunctional Aldose Reductase Inhibitors Based on Quinoxalinones-Reference-Cited by-同舟云学术

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Design and Synthesis of Potent and Multifunctional Aldose Reductase Inhibitors Based on Quinoxalinones

Published:2015-02-03 Issue:3 Volume:58 Page:1254-1267
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Qin Xiangyu¹,Hao Xin¹,Han Hui¹,Zhu Shaojuan¹,Yang Yanchun¹,Wu Bobin¹,Hussain Saghir¹,Parveen Shagufta¹,Jing Chaojun¹,Ma Bing¹,Zhu Changjin¹

Affiliation:

1. Department of Applied Chemistry, Beijing Institute of Technology, Zhongguancun South Street, 100081 Beijing, China

Funder

Ministry of Education of the People's Republic of China

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Beijing Municipal Science and Technology Commision

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501484b

Reference53 articles.

1. A novel polymorphism in the aldose reductase gene promoter region is strongly associated with diabetic retinopathy in adolescents with type 1 diabetes.

2. Aldose Reductase Enzyme and its Implication to Major Health Problems of the 21st Century

3. Biochemistry and molecular cell biology of diabetic complications

4. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat: Implications for the binding of cyclic imide inhibitors

5. Aldose reductase: A novel therapeutic target for inflammatory pathologies

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