NAD<sup>+</sup> Kinase Enzymes Are Reversible, and NAD<sup>+</sup> Product Inhibition Is Responsible for the Observed Irreversibility of the Human Enzyme-Reference-Cited by-同舟云学术

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NAD⁺ Kinase Enzymes Are Reversible, and NAD⁺ Product Inhibition Is Responsible for the Observed Irreversibility of the Human Enzyme

Published:2022-08-19 Issue:17 Volume:61 Page:1862-1873
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Willett Emma¹,Jiang Virginia¹,Koder Ronald L.²³,Banta Scott¹^ORCID

Affiliation:

1. Department of Chemical Engineering, Columbia University, New York, New York 10027, United States

2. Department of Physics, The City College of New York, New York, New York 10031, United States

3. Graduate Programs of Physics, Biology, Chemistry and Biochemistry, The Graduate Center of CUNY, New York, New York 10016, United States

Funder

Division of Chemical, Bioengineering, Environmental, and Transport Systems

New York State Energy Research and Development Authority

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00386

Reference60 articles.

1. NAD + metabolism: Bioenergetics, signaling and manipulation for therapy

2. Keeping the balance in NAD metabolism

3. The phosphate makes a difference: cellular functions of NADP

4. Enzymology of NAD+ homeostasis in man

5. Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues

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