1. Business Development, Astellas Pharma Inc., Tsukuba, Ibaraki 305-8585, Japan
2. Applied Research & Operations, Astellas Pharma Inc., Tsukuba, Ibaraki 305-8585, Japan
3. Meyer Cancer Center, Department of Medicine, Weill Cornell Medical College, New York, New York 10065, United States
4. Department of Molecular & Integrative Physiology, Department of Internal Medicine, Division of Gastroenterology, and Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States