Determining the Stoichiometry of a Protein–Polymer Conjugate Using Multisignal Sedimentation Velocity Analytical Ultracentrifugation-Reference-Cited by-同舟云学术

Determining the Stoichiometry of a Protein–Polymer Conjugate Using Multisignal Sedimentation Velocity Analytical Ultracentrifugation

Published:2021-04-13 Issue:5 Volume:32 Page:942-949
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Clardy Susan M.¹^ORCID,Lee David H.¹,Schuck Peter²^ORCID

Affiliation:

1. Mersana Therapeutics Inc., Cambridge, Massachusetts 02139, United States

2. Dynamics of Macromolecular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892, United States

Funder

Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health

Mersana Therapeutics

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.1c00095

Reference30 articles.

1. Molecular Sieving on the Surface of a Nano-Armored Protein

2. Charge-Preserving Atom Transfer Radical Polymerization Initiator Rescues the Lost Function of Negatively Charged Protein–Polymer Conjugates

3. Next generation protein-polymer conjugates

4. Some Lessons Learned From a Comparison Between Sedimentation Velocity Analytical Ultracentrifugation and Size Exclusion Chromatography to Characterize and Quantify Protein Aggregates

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