125I-Tetrazines and Inverse-Electron-Demand Diels–Alder Chemistry: A Convenient Radioiodination Strategy for Biomolecule Labeling, Screening, and Biodistribution Studies
Author:
Affiliation:
1. Department of Chemistry and Chemical Biology and ‡Centre for Probe Development and Commercialization, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4M1
Funder
Natural Sciences and Engineering Research Council of Canada
Ontario Institute for Cancer Research
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.5b00609
Reference43 articles.
1. Blood-Brain Barrier Molecular Trojan Horse Enables Imaging of Brain Uptake of Radioiodinated Recombinant Protein in the Rhesus Monkey
2. Comparative in vivo analysis of the atherosclerotic plaque targeting properties of eight human monoclonal antibodies
3. Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody
4. Radioiodination of an endotoxin·MD-2 complex generates a novel sensitive, high-affinity ligand for TLR4
5. Biodistribution of [125I]-labeled therapeutic proteins: Application in protein drug development beyond oncology**All authors are current or former employees of Wyeth, Inc.
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