Topical Administration of an Apoptosis Inducer Mitigates Bleomycin-Induced Skin Fibrosis

Author:

Huda Md Nurul1ORCID,Borrego Edgar A.23,Guerena Cristina D.23,Varela-Ramirez Armando23,Aguilera Renato J.23ORCID,Hamadani Christine M.4,Tanner Eden E. L.4ORCID,Badruddoza Abu Zayed Md5ORCID,Agarwal Sandeep K.6,Nurunnabi Md13ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy, University of Texas at El Paso, El Paso, Texas 79902, United States

2. Department of Biological Sciences, College of Sciences, University of Texas at El Paso, El Paso, Texas 79956, United States

3. Border Biomedical Research Center, University of Texas at El Paso, El Paso, Texas 79956, United States

4. Department of Chemistry & Biochemistry, The University of Mississippi, University, Mississippi 38677, United States

5. Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States

6. Department of Medicine, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, Texas 77030, United States

Funder

Cancer Prevention and Research Institute of Texas

U.S. Department of Health and Human Services

College of Liberal Arts, University of Mississippi

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Reference58 articles.

1. American College of Rheumatology. Scleroderma; 2022.

2. Aberrant immune response with consequent vascular and connective tissue remodeling – causal to scleroderma and associated syndromes such as Raynaud phenomenon and other fibrosing syndromes?

3. Skin fibrosis: Models and mechanisms

4. John Hopkins Medicine. Scleroderma Treatment, 2022.

5. Michigan Health Lab. Systemic Scleroderma Treatments: Where Are We Now?, 2022.

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