A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach-Reference-Cited by-同舟云学术

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A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach

Published:2024-07-15 Issue:8 Volume:7 Page:2439-2451
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Armstrong Georgina B.¹²^ORCID,Lewis Alan³,Shah Vidhi⁴,Taylor Paul¹,Jamieson Craig J.⁵^ORCID,Burley Glenn A.⁵^ORCID,Lewis William¹,Rattray Zahra²^ORCID

Affiliation:

1. Drug Substance Development, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

2. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, U.K.

3. Computational and Modelling Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

4. Large Molecule Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

5. Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, U.K.

Funder

Engineering and Physical Sciences Research Council

GlaxoSmithKline

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.4c00271

Reference48 articles.

1. How to select IgG subclasses in developing anti-tumor therapeutic antibodies

2. Coming together at the hinges: Therapeutic prospects of IgG3

3. Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3)

4. IgG3 subclass antibodies recognize antigenically drifted influenza viruses and SARS-CoV-2 variants through efficient bivalent binding

5. Role of IgG3 in Infectious Diseases

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