Discovery of Isoindoline Amide Derivatives as Potent and Orally Bioavailable ADAMTS-4/5 Inhibitors for the Treatment of Osteoarthritis-Reference-Cited by-同舟云学术

Discovery of Isoindoline Amide Derivatives as Potent and Orally Bioavailable ADAMTS-4/5 Inhibitors for the Treatment of Osteoarthritis

Published:2022-06-22 Issue:7 Volume:5 Page:458-467
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Zhao Peng¹^ORCID,Liu Dong¹,Song Chunying¹,Li Di¹,Zhang Xinzhu¹,Horecny Ivana¹,Zhang Fengqi¹,Yan Yuna²,Zhuang Linghang¹,Li Jing¹,Liu Suxing¹,Mao Yuchang²,Feng Jun²,Liu Jian¹^ORCID,Tao Weikang²

Affiliation:

1. Eternity Bioscience Inc., 6 Cedarbrook Drive, Cranbury, New Jersey 08512, United States

2. Shanghai Hengrui Pharmaceutical Co. Ltd., 279 Wenjing Road, Shanghai 200245, China

Funder

Eternity Bioscience Inc

Shanghai Hengrui Pharmaceutical Co. Ltd

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00023

Reference42 articles.

1. From Pathogenesis to Therapy in Knee Osteoarthritis: Bench-to-Bedside

2. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies

3. Osteoarthritis and Ageing

4. Inflammation in osteoarthritis

5. The Development of Disease-Modifying Therapies for Osteoarthritis (DMOADs): The Evidence to Date

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