Highly Drug-Resistant HIV-1 Protease Mutant PRS17 Shows Enhanced Binding to Substrate Analogues-Reference-Cited by-同舟云学术

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Highly Drug-Resistant HIV-1 Protease Mutant PRS17 Shows Enhanced Binding to Substrate Analogues

Published:2019-05-17 Issue:5 Volume:4 Page:8707-8719
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Agniswamy Johnson¹,Kneller Daniel W.¹,Brothers Rowan²,Wang Yuan-Fang¹,Harrison Robert W.³,Weber Irene T.¹²^ORCID

Affiliation:

1. Department of Biology, Georgia State University, P.O. Box 4010, Atlanta, Georgia 30302, United States

2. Department of Chemistry, Georgia State University, P.O. Box 3965, Atlanta, Georgia 30302, United States

3. Department of Computer Science, Georgia State University, P.O. Box 5060, Atlanta, Georgia 30302, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.9b00683

Reference65 articles.

1. International AIDS Society global scientific strategy: towards an HIV cure 2016

2. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS

3. Defeating AIDS—advancing global health

4. HIV-1 Protease: Structural Perspectives on Drug Resistance

5. Human immunodeficiency virus-1 protease. 1. Initial velocity studies and kinetic characterization of reaction intermediates by oxygen-18 isotope exchange

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2. Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation;European Journal of Medicinal Chemistry;2023-07

3. HIV-1 protease with 10 lopinavir and darunavir resistance mutations exhibits altered inhibition, structural rearrangements and extreme dynamics;Journal of Molecular Graphics and Modelling;2022-12

4. Multiple Molecular Dynamics Simulations and Energy Analysis Unravel the Dynamic Properties and Binding Mechanism of Mutants HIV-1 Protease with DRV and CA-p2;Microbiology Spectrum;2022-04-27

5. Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands;ChemMedChem;2022-03-04

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