Thieno[2,3-b]thiophene Derivatives as Potential EGFRWT and EGFRT790M Inhibitors with Antioxidant Activities: Microwave-Assisted Synthesis and Quantitative In Vitro and In Silico Studies-Reference-Cited by-同舟云学术

Thieno[2,3-b]thiophene Derivatives as Potential EGFR^WT and EGFRT^790M Inhibitors with Antioxidant Activities: Microwave-Assisted Synthesis and Quantitative In Vitro and In Silico Studies

Published:2022-12-03 Issue:49 Volume:7 Page:45535-45544
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Ahmed Sanaa A.¹,Kamel Moumen S.²,Aboelez Moustafa O.³^ORCID,Ma Xiang⁴,Al-Karmalawy Ahmed A.⁵^ORCID,Mousa Sayed A. S.⁶,Shokr Elders Kh.⁷,Abdel-Ghany H.²,Belal Amany⁸⁹^ORCID,El Hamd Mohamed A.¹⁰¹¹,Al Shehri Zafer S.¹²,El Aleem Ali Ali El-Remaily Mahmoud Abd²^ORCID

Affiliation:

1. Department of Pharmacology, Faculty of Medicine, Sohag University, Sohag82524, Egypt

2. Department of Chemistry, Faculty of Science, Sohag University, Sohag82524, Egypt

3. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag82524, Egypt

4. School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430030, China

5. Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, 6th of October City, Giza12566, Egypt

6. Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut Branch, Assiut71524, Egypt

7. Department of Physics, Faculty of Science, Sohag University, Sohag82524, Egypt

8. Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef62514, Egypt

9. Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif21944, Saudi Arabia

10. Department of Pharmaceutical Sciences, College of Pharmacy, Shaqra University, Shaqra11961, Saudi Arabia

11. Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, South Valley University, Qena83523, Egypt

12. Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, Shaqra11961, Saudi Arabia

Funder

Umm Al-Qura University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.2c06219

Reference66 articles.

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4. Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: In Vitro, in Vivo, molecular docking, molecular dynamics, and SAR studies

5. Design, synthesis, biological evaluation, and SAR studies of novel cyclopentaquinoline derivatives as DNA intercalators, topoisomerase II inhibitors, and apoptotic inducers

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