Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies-Reference-Cited by-同舟云学术

Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies

Published:2022-01-20 Issue:4 Volume:7 Page:3775-3795
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Mehmood Rabia¹,Sadiq Amina¹,Alsantali Reem I.²,Mughal Ehsan Ullah³^ORCID,Alsharif Meshari A.⁴,Naeem Nafeesa³,Javid Asif³,Al-Rooqi Munirah M.⁴,Chaudhry Gul-e-Saba⁵⁶,Ahmed Saleh A.⁴⁷^ORCID

Affiliation:

1. Department of Chemistry, Govt. College Women University, Sialkot 51300, Pakistan

2. Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

3. Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan

4. Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia

5. Institute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Nerus 21030, Terengganu, Malaysia

6. Microbiology and Biotechnology Research Lab, Fatima Jinnah Women University, Rawalpindi 23451, Pakistan

7. Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt

Funder

Higher Education Commision, Pakistan

Taif University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.1c06694

Reference98 articles.

1. 5-Bromo-2-aryl benzimidazole derivatives as non-cytotoxic potential dual inhibitors of α -glucosidase and urease enzymes

2. Synthesis of new arylhydrazide bearing Schiff bases/thiazolidinone: α-Amylase, urease activities and their molecular docking studies

3. Benzenesulfonohydrazides inhibiting urease: Design, synthesis, their in vitro and in silico studies

4. 3-Arylpropionylhydroxamic acid derivatives as Helicobacter pylori urease inhibitors: Synthesis, molecular docking and biological evaluation

5. Synthesis, biological evaluation and molecular docking of N-phenyl thiosemicarbazones as urease inhibitors

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