Lonidamine Increases the Cytotoxic Effect of 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea via Energy Inhibition, Disrupting Redox Homeostasis, and Downregulating MGMT Expression in Human Lung Cancer Cell Line-Reference-Cited by-同舟云学术

Lonidamine Increases the Cytotoxic Effect of 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea via Energy Inhibition, Disrupting Redox Homeostasis, and Downregulating MGMT Expression in Human Lung Cancer Cell Line

Published:2024-08-17 Issue: Volume: Page:
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Fan Tengjiao¹²,Shen Lin³,Huang Yaxin²,Wang Xin⁴,Zhao Lijiao²^ORCID,Zhong Rugang²,Wang Peng⁵,Sun Guohui²^ORCID

Affiliation:

1. Department of Medical Technology, Beijing Pharmaceutical University of Staff and Workers, Beijing 100079, P. R. China

2. Beijing Key Laboratory of Environment & Viral Oncology, College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, P. R. China

3. Department of Dermatology, the First Medical Center of PLA General Hospital, Beijing 100853, P. R. China

4. Department of Clinical Trials Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100029, P. R. China

5. Department of Neurosurgery, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, P. R. China

Funder

Natural Science Foundation of Beijing Municipality

National Natural Science Foundation of China

Beijing Municipal Education Commission

Beijing Municipality

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.4c00641

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