Discovery of the First N-Hydroxycinnamamide-Based Histone Deacetylase 1/3 Dual Inhibitors with Potent Oral Antitumor Activity-Reference-Cited by-同舟云学术

Discovery of the First N-Hydroxycinnamamide-Based Histone Deacetylase 1/3 Dual Inhibitors with Potent Oral Antitumor Activity

Published:2014-04-15 Issue:8 Volume:57 Page:3324-3341
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Xiaoyang¹,Inks Elizabeth S.²,Li Xiaoguang¹,Hou Jinning¹,Chou C. James²,Zhang Jian¹,Jiang Yuqi¹,Zhang Yingjie¹,Xu Wenfang¹

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy, Shandong University, Ji’nan, Shandong 250012, P. R. China

2. Department of Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401877m

Reference32 articles.

1. Gene Silencing in Cancer in Association with Promoter Hypermethylation

2. The Structure and Function of Histone Deacetylases: The Target for Anti-cancer Therapy

3. Epigenetics and cancer treatment

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5. Sirtuin 1 (SIRT1)

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