Lipid Nanocarriers of a Lipid-Conjugated Estrogenic Derivative Inhibit Tumor Growth and Enhance Cisplatin Activity against Triple-Negative Breast Cancer: Pharmacokinetic and Efficacy Evaluation

Author:

Andey Terrick1,Sudhakar Godeshala2,Marepally Srujan3,Patel Apurva4,Banerjee Rajkumar2,Singh Mandip4

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy, Massachusetts College of Pharmacy and Health Sciences, 19 Foster Street, Worcester, Massachusetts 01608, United States

2. Biomaterials Group, CSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad, Andhra Pradesh 500007, India

3. Institute for Stem Cell Biology and Regenerative Medicine (inStem), NCBS-TIFR, UAS-GKVK, Bengaluru, Karnataka 560067, India

4. Department of Pharmaceutics, College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1520 South Martin Luther King Jr. Boulevard, Tallahassee, Florida 32307, United States

Funder

U.S. Department of Defense

National Institute of General Medical Sciences

National Institute on Minority Health and Health Disparities

Department of Science and Technology, Ministry of Science and Technology

Council of Scientific and Industrial Research

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference55 articles.

1. Prospective identification of tumorigenic breast cancer cells

2. Comprehensive molecular portraits of human breast tumours

3. American Cancer Society. Cancer Facts & Figures 2014.http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2014/index(accessed September 2, 2014).

4. Cancer statistics, 2013

5. Identification of FDA-approved Drugs Targeting Breast Cancer Stem Cells Along With Biomarkers of Sensitivity

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