Discovery of CP-690,550: A Potent and Selective Janus Kinase (JAK) Inhibitor for the Treatment of Autoimmune Diseases and Organ Transplant Rejection-Reference-Cited by-同舟云学术

Discovery of CP-690,550: A Potent and Selective Janus Kinase (JAK) Inhibitor for the Treatment of Autoimmune Diseases and Organ Transplant Rejection

Published:2010-11-24 Issue:24 Volume:53 Page:8468-8484
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Flanagan Mark E.¹,Blumenkopf Todd A.²,Brissette William H.³,Brown Matthew F.¹,Casavant Jeffrey M.¹,Shang-Poa Chang⁴,Doty Jonathan L.⁵,Elliott Eileen A.¹,Fisher Michael B.⁶,Hines Michael¹,Kent Craig¹,Kudlacz Elizabeth M.²,Lillie Brett M.¹,Magnuson Kelly S.²,McCurdy Sandra P.¹,Munchhof Michael J.¹,Perry Bret D.¹,Sawyer Perry S.¹,Strelevitz Timothy J.¹,Subramanyam Chakrapani¹,Sun Jianmin¹,Whipple David A.⁷,Changelian Paul S.⁸

Affiliation:

1. Groton Laboratories, Pfizer Global Research & Development, Eastern Point Road, Groton, Connecticut 06340, United States

2. Pfizer Global Research & Development, 50 Pequot Avenue, New London, Connecticut 06320, United States

3. Yale University, New Haven, Connecticut 06520, United States

4. Department of Statistics, University of Connecticut, 215 Glenbrook Road U-4120, Storrs, Connecticut 06269, United States

5. Hill Road, East Lyme, Connecticut 06333, United States

6. Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, P.O. Box 368, Ridgefield, Connecticut 06877, United States

7. Del Shankel Structural Biology Center, University of Kansas, 2034 Becker Drive, Lawrence, Kansas 66047, United States

8. Lycera Corporation, 46701 North Commerce Center Drive, Plymouth, Michigan 48170, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1004286

Reference43 articles.

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