Anti-CD22-MCC-DM1 and MC-MMAF Conjugates: Impact of Assay Format on Pharmacokinetic Parameters Determination-Reference-Cited by-同舟云学术

Anti-CD22-MCC-DM1 and MC-MMAF Conjugates: Impact of Assay Format on Pharmacokinetic Parameters Determination

Published:2008-07-19 Issue:8 Volume:19 Page:1673-1683
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Stephan Jean-Philippe¹,Chan Pamela¹,Lee Chien¹,Nelson Christopher¹,Elliott James Michael¹,Bechtel Charity¹,Raab Helga¹,Xie David¹,Akutagawa Jon¹,Baudys Jakub¹,Saad Ola¹,Prabhu Saileta¹,Wong Wai Lee T.¹,Vandlen Richard¹,Jacobson Fred¹,Ebens Allen¹

Affiliation:

1. Departments of Assay and Automation Technology, Protein Analytical Chemistry, Protein Chemistry, Early Development Pharmacokinetic and Pharmacodynamic Sciences, BioAnalytical Research and Development, and Translational Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc800059t

Reference27 articles.

1. Targeted drug conjugates: principles and progress

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4. Pharmacokinetics and Biodistribution of the Antitumor Immunoconjugate, Cantuzumab Mertansine (huC242-DM1), and Its Two Components in Mice

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