Dual-Layer Surface Coating of PLGA-Based Nanoparticles Provides Slow-Release Drug Delivery To Achieve Metronomic Therapy in a Paclitaxel-Resistant Murine Ovarian Cancer Model

Author:

Amoozgar Zohreh12,Wang Lei12,Brandstoetter Tania12,Wallis Samuel S.12,Wilson Erin M.12,Goldberg Michael S.12

Affiliation:

1. Department of Cancer Immunology & AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States

2. Department of Microbiology & Immunobiology, Harvard Medical School, Boston, Massachusetts 02215, United States

Funder

Ovarian Cancer Research Fund

Aid for Cancer Research

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

Reference36 articles.

1. Cancer Facts & Figures;American Cancer Society,Atlanta, GA, 2013.http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-036845.pdf.

2. Ovarian cancer

3. Repopulation of tumour cells between cycles of chemotherapy: a neglected factor

4. The epigenetics of ovarian cancer drug resistance and resensitization

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