Access to Imidazolidine-Fused Sulfamidates and Sulfamides Bearing a Quaternary Center via 1,3-Dipolar Cycloaddition of Nonstabilized Azomethine Ylides-Reference-Cited by-同舟云学术

Access to Imidazolidine-Fused Sulfamidates and Sulfamides Bearing a Quaternary Center via 1,3-Dipolar Cycloaddition of Nonstabilized Azomethine Ylides

Published:2017-03-27 Issue:7 Volume:82 Page:3597-3604
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Laha Joydev K.¹^ORCID,Jethava Krupal P.¹

Affiliation:

1. Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research, S. A. S. Nagar, Punjab 160062, India

Funder

Science and Engineering Research Board

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.7b00116

Reference47 articles.

1. Bioisosterism: A Useful Strategy for Molecular Modification and Drug Design

2. Carboxylic Acid (Bio)Isosteres in Drug Design

3. A Novel Regio- and Stereoselective Synthesis of Sulfamidates from 1,2-Diols Using Burgess and Related Reagents: A Facile Entry into β-Amino Alcohols We thank Professor K. Barry Sharpless for the gracious donation of several of the starting diol substrates. We also thank Drs. D. H. Huang, G. Suizdak, and R. Chadja for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, predoctoral fellowships from the National Science Foundation and Pfizer (S.A.S.), a postdoctoral fellowship from The Skaggs Institute for Chemical Biology (X.H.), and grants from American Biosciences, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffman-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough.