Unexpected Substituent Effects in Spiro-Compound Formation: Steering N-Aryl Propynamides and DMSO toward Site-Specific Sulfination in Quinolin-2-ones or Spiro[4,5]trienones-Reference-Cited by-同舟云学术

Unexpected Substituent Effects in Spiro-Compound Formation: Steering N-Aryl Propynamides and DMSO toward Site-Specific Sulfination in Quinolin-2-ones or Spiro[4,5]trienones

Published:2021-06-29 Issue:14 Volume:86 Page:9490-9502
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Li Xiaoxian¹^ORCID,Wang Yuanxun²,Ouyang Yaxin¹,Yu Zhenyang¹,Zhang Beibei¹,Zhang Jingran¹,Shi Haofeng¹,Zuilhof Han¹³⁴^ORCID,Du Yunfei¹^ORCID

Affiliation:

1. School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China

2. National Institute of Biological Sciences, Beijing, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206, China

3. Laboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6703 WE Wageningen, The Netherlands

4. Department of Chemical and Materials Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia

Funder

Tianjin University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c00775

Reference94 articles.

1. Modified synthesis and antiangiogenic activity of linomide

2. Synthesis and Biological Evaluation of New 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for Treatment of Autoimmune Disorders: Structure−Activity Relationship

3. Novel, Potent, and Orally Active Substance P Antagonists: Synthesis and Antagonist Activity of N-Benzylcarboxamide Derivatives of Pyrido[3,4-b]pyridine

4. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors

5. Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist

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