Amidative Cyclization of Alkynyl Esters to Access Pyrazin-1(2<i>H</i>)-ones: Application to the Synthesis of Peramine and Dibromophakellin-Reference-Cited by-同舟云学术

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Amidative Cyclization of Alkynyl Esters to Access Pyrazin-1(2H)-ones: Application to the Synthesis of Peramine and Dibromophakellin

Published:2023-12-05 Issue:24 Volume:88 Page:17330-17344
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Gangnale Laxmikant D.¹²,Miriyala Satya Ravi Teja¹²,Pasunooti Kalyan Kumar³⁴,Reddy D. Srinivasa¹²³^ORCID

Affiliation:

1. Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India

3. Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India

4. Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, United States

Funder

University Grants Commission

Science and Engineering Research Board

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c02157

Reference70 articles.

1. Propargylamine: an important moiety in drug discovery

2. Propargylamine as functional moiety in the design of multifunctional drugs for neurodegenerative disorders: MAO inhibition and beyond

3. Synthesis and Reactivity of Propargylamines in Organic Chemistry

4. Recent Advances in Reactions of Propargylamines

5. In Situ Allene Formation via Alkyne Tautomerization to Promote [4 + 2]-Cycloadditions with a Pendant Alkyne or Nitrile

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