Theoretical Insight into the Mechanism of Cu(I)-Catalyzed [2 + 2 + 1] Cycloaddition to β-Pyrrolinones: Azaheterocycle Formation and Assisted Dehydrogenation with Solvent MeNO<sub>2</sub>-Reference-Cited by-同舟云学术

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Theoretical Insight into the Mechanism of Cu(I)-Catalyzed [2 + 2 + 1] Cycloaddition to β-Pyrrolinones: Azaheterocycle Formation and Assisted Dehydrogenation with Solvent MeNO₂

Published:2023-07-19 Issue:15 Volume:88 Page:10670-10681
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Ma Nana¹^ORCID,Zhou Lanxin¹,Li Yameng¹,Wu Hao¹,Li Shujun¹,Zhang Guisheng¹^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education; NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Henan Normal University, Xinxiang, Henan, 453007, China

Funder

Natural Science Foundation of Henan Province

National Natural Science Foundation of China

Program for Science & Technology Innovation Talents in Universities of Henan Province

Henan Provincial Key Laboratory of Organic Functional Molecule and Drug Innovation, Henan Normal University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c00727

Reference44 articles.

1. Structure–Activity Relationship Studies of Pyrrolone Antimalarial Agents

2. Pyrrolinone-Based Peptidomimetics.“Let the Enzyme or Receptor be the Judge”

3. Design, Synthesis, and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors

4. Design, Synthesis, and Evaluation of a Pyrrolinone−Peptide Hybrid Ligand for the Class II MHC Protein HLA-DR1

5. Total Synthesis of the Kopsia lapidilecta Alkaloid (±)-Lapidilectine B

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