A Novel Class of in Vivo Active Anticancer Agents: Achiral seco-Amino- and seco-Hydroxycyclopropylbenz[e]indolone (seco-CBI) Analogues of the Duocarmycins and CC-1065-Reference-Cited by-同舟云学术

A Novel Class of in Vivo Active Anticancer Agents: Achiral seco-Amino- and seco-Hydroxycyclopropylbenz[e]indolone (seco-CBI) Analogues of the Duocarmycins and CC-1065

Published:2005-05-05 Issue:11 Volume:48 Page:3903-3918
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sato Atsushi¹,McNulty LuAnne¹,Cox Kari¹,Kim Susan¹,Scott Adrienne¹,Daniell Kristen¹,Summerville Kaitlin¹,Price Carly¹,Hudson Stephen¹,Kiakos Konstantinos¹,Hartley John A.¹,Asao Tetsuji¹,Lee Moses¹

Affiliation:

1. Department of Chemistry, Furman University, 3300 Poinsett Highway, Greenville, South Carolina 29613, Cancer Research UK Drug−DNA Interactions Research Group, Department of Oncology, University College London, 91 Riding House Street, London, W1W 7BS, U.K., and Taiho Pharmaceutical Co., Ltd., 1-27, Misugidai Hanno-City, Saitama, 357-8527, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050179u

Reference65 articles.

1. CC-1065 and the Duocarmycins: Understanding their Biological Function through Mechanistic Studies

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