1. Contribution from the School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK, Centre for Chemical Dynamics, University of Leeds, Leeds, LS2 9JT, UK, School of Biochemistry and Microbiology, University of Leeds, Leeds, LS2 9JT, UK, AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire, SK10 4TG, UK, and Protein Phosphorylation Laboratory, London Research Institute, 44 Lincoln's Inn Fields, London WC2 3PX...